Ketogenic Diet Shows Promise as Epigenetic Therapy for SETD1B Epilepsy
3 Articles
3 Articles
For most people, ketogenic diet is associated with weight loss. However, in pediatric neurology, the same metabolic idea has a much more serious use. A carefully calculated ketogenic diet can reduce the frequency of seizures in some children with epilepsy, especially when medicines fail to provide sufficient control. In certain forms of epilepsy, [...]
Ketogenic Diet Shows Promise as Epigenetic Therapy for SETD1B Epilepsy
In a striking demonstration of how diet can reach into the deepest layers of gene regulation, clinicians and researchers in Australia have reported that a high-fat ketogenic diet produced sustained seizure control in a young boy with a rare genetic epilepsy—while single-cell analysis of his blood showed that the diet appeared to reverse widespread molecular abnormalities linked to his condition. The case, published in Annals of Clinical and Tran…
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