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JCI Insight High-dose influenza vaccine augments serological and cellular immunity of older people with HIV

Summary by jci.org
BACKGROUND High-dose influenza vaccine, containing 4 times more antigen than the standard dose, is recommended for people 65 years or older, but there is a knowledge gap surrounding its effect in people with HIV (PWH), who remain more vulnerable to serious influenza infections than people without HIV (PWoH) despite virological suppression. Our primary goal was to assess whether the high-dose vaccine improves antibody responses in PWH, especially…
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jci.org broke the news on Saturday, May 2, 2026.
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