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Inside Crimean–Congo Hemorrhagic Fever Virus Polymerase Structure
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Inside Crimean–Congo Hemorrhagic Fever Virus Polymerase Structure
In a significant breakthrough for virology and antiviral drug development, researchers have unveiled the high-resolution cryogenic electron microscopy (cryo-EM) structures of the RNA-dependent RNA polymerase (RdRp) of the Crimean–Congo haemorrhagic fever virus (CCHFV). This viral enzyme, also known as the L protein, is a critical component in the replication machinery of the virus, belonging to […]
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