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Inflammation linked to brain reward dysfunction in American Indians with depression

Summary by PsyPost
Recent research indicates that bodily inflammation may disrupt the brain’s ability to process rewards and risks in American Indian adults who have experienced depression. The study found that higher levels of specific inflammatory markers in the blood corresponded with reduced activity in brain regions essential for motivation. These findings were published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. Major Depressive Disor…

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PsyPost broke the news in on Monday, December 22, 2025.
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