IMPA2 Ameliorates High-Fat Diet-Induced Obesity by Enhancing Adaptive Thermogenesis in a Ca2+-activated Mitochondrial Biogenesis Pathway

IMPA2 Ameliorates High-Fat Diet-Induced Obesity by Enhancing Adaptive Thermogenesis in a Ca2+-activated Mitochondrial Biogenesis Pathway

The identification of thermogenic adipocytes in humans proves that enhanced adaptive thermogenesis may help mitigate obesity. Although some evidence suggests a role for IMPA2 in cellular metabolism, its specific impact on obesity and the underlying mechanisms remain underexplored. High-fat-die...