Tumours vulnerable to immunotherapy could be hunted with algorithm developed in Cambridge

Tumours vulnerable to immunotherapy could be hunted with algorithm developed in Cambridge

Development could help enable personalised treatment.

New AI Tool Hones in on Tumor’s Vulnerabilities

An algorithm, PRRDetect, that more accurately points out key mutations to target in tumors was developed by researchers at the University of Cambridge and NIHR Cambridge Biomedical Research Centre. Knowing a tumor’s very specific vulnerabilities could improve outcomes, including with immunotherapy. The team wrote, “Despite their deleterious effects, small insertions and deletions (InDels) have received far less attention than substitutions.”  Th…

Immunotherapy Treatment Options in High-Risk or Locally Advanced/Metastatic Non-melanoma and Melanoma: An Evolving Treatment Landscape

On April 4, 2025, a select group of international experts in dermatologic oncology participated in a live workshop to discuss treatment options in high-risk or locally advanced/metastatic melanoma and non-melanoma skin cancers in an evolving treatment landscape. Caroline Robert, MD, PhD, led the discussion, obtaining perspectives on the available evidence about immunotherapy options and insights into treatment preferences for high-risk cutaneous…