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Immunotherapy drug doubles survival rate for head and neck cancer in breakthrough trial

  • A global trial presented at ASCO shows pembrolizumab helps head and neck cancer patients stay cancer-free for five years versus 2.5 years with standard care.
  • Researchers tested pembrolizumab, an immunotherapy drug, after over 20 years of little progress in treating newly-diagnosed, locally-advanced head and neck cancer.
  • The Keynote-689 trial, conducted at 192 sites in 24 countries with 714 patients, demonstrated that pembrolizumab lowered the risk of the cancer recurring in a different location by 10% after three years.
  • Professor Kevin Harrington stated that pembrolizumab significantly extends the period patients remain free from disease, providing benefits that last several years beyond those achieved by existing standard treatments, and this improvement applies to all patients regardless of their immune marker status.
  • These findings suggest pembrolizumab could improve survival for thousands with head and neck cancer, potentially changing treatment standards and reducing cancer spread risks significantly.
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NewsGroove Uk broke the news in on Friday, May 30, 2025.
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