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Immune 'switch' identified as a potential target to curb chronic inflammation in cirrhosis

Summary by Medical Xpress
Chronic liver inflammation is one of the most serious complications associated with liver cirrhosis. Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified a molecular mechanism that acts as an immune "switch" and could potentially be harnessed to slow disease progression. The findings show that the liver protein LSECtin, which is progressively lost as cirrhosis advances, plays a key protective role by restraining p…

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Chronic liver inflammation is one of the most serious problems associated with liver cirrhosis. The Hepatic and Intestinal Immunobiology Group of Miguel Hernández de Elche University (UMH) has discovered a molecular mechanism that acts as an ‘interruptor’ and that, potentially, could be used to slow the progress of the disease. The study, published in JHEP Reports and carried out in mice and tissue samples, points out that LSECtin protein—presen…

Researchers from the Hepatic and Intestinal Immunobiology Group of the Miguel Hernández de Elche University (UMH) have discovered a "key" immune mechanism that could reduce chronic inflammation in liver cirrhosis, one of the "most serious" problems associated with this pathology. Specifically, it acts as an "interruptor" and, potentially, could be used to slow the progress of the disease.

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diarioestrategia.cl broke the news in on Wednesday, December 10, 2025.
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