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Combining long- and short-read sequencing in single cells reveals new mRNAs in neurodegenerative diseases

Summary by Science Daily

Researchers have combined two sequencing technologies in single cells to find new differences in mRNAs resulting from Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease.

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Science Daily

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Medical Xpress

Combining long- and short-read sequencing in single cells reveals new mRNAs in neurodegenerative diseases

Researchers have combined two sequencing technologies in single cells to find new differences in mRNAs resulting from Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease.

3 months ago·United States

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Newswise

Combining long- and short-read sequencing in singl

Researchers led by Jerold Chun MD, PhD, professor in the Degenerative Diseases Program at Sanford Burnham Prebys, published results December 10, 2024, in eNeuro from combining two sequencing technologies in single cells to find new differences in mRNAs resulting from Alzheimer's disease, dementia with Lewy bodies and Parkinson’s disease.

3 months ago·Charlottesville, United States

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Stemwell Science News

Immune Mechanisms and Shared Immune Targets in Neurodegenerative Diseases

The authors discuss how microglia, monocytes, and T cells contribute to the pathogenesis of MS, Alzheimer’s disease, ALS, and Parkinson disease, and their potential as shared therapeutic targets across these diseases. [Nature Reviews Neurology] Full Article

3 months ago

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