How Huntington’S Disease Affects Different Neurons

How Huntington's disease affects different neurons: A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement.

Neuroscientists find two distinct cell populations in the striatum are affected differently by Huntington's disease. They believe neurodegeneration of one of these populations leads to motor impairments, while damage to the other population, located in a structure called the striosome, may account for the mood disorders that are often see in the early stages of the disease.

How Huntington’S Disease Affects Different Neurons

In patients with Huntington's disease, neurons in a part of the brain called the striatum are among the hardest-hit.

How Huntington's disease affects different neurons

In patients with Huntington's disease, neurons in a part of the brain called the striatum are among the hardest-hit. Degeneration of these neurons contributes to patients' loss of motor control, which is one of the major hallmarks of the disease.

How Huntington’s disease affects different neurons - MIT McGovern Institute

In patients with Huntington’s disease, neurons in a part of the brain called the striatum are among the hardest-hit. Degeneration of these neurons contributes to patients’ loss of motor control, which is one of the major hallmarks of the disease. Neuroscientists at MIT have now shown that two distinct cell populations in the striatum are […]