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How cells 'back up' DNA replication to survive severe damage

Summary by Phys.org
Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks (ICLs), which chemically bind the two strands of DNA together and block the machinery responsible for copying the genome.

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How cells 'back up' DNA replication to survive severe damage

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks (ICLs), which chemically bind the two strands of DNA together and block the machinery responsible for copying the genome.

·United Kingdom
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Phys.org broke the news in United Kingdom on Thursday, May 7, 2026.
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