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Banged-up 49ers Looking for Smoother Sailing at Saints
Both teams face key injuries with 49ers' Brock Purdy and Saints' offensive linemen Fuaga and Penning uncertain for Week 2, impacting lineup and strategy decisions.
- The San Francisco 49ers are set to play the New Orleans Saints on Sunday, September 14, 2025, in New Orleans at 1 p.m.
- The 49ers are dealing with significant injuries, as tight end George Kittle has been sidelined due to a hamstring issue and placed on injured reserve, while quarterback Brock Purdy's status remains uncertain because of toe and shoulder injuries.
- The Saints, who lost their season opener to the Arizona Cardinals, also contend with injuries to offensive linemen Taliese Fuaga and Trevor Penning and season-ending surgery for safety Julian Blackmon.
- The 49ers lead the all-time series 50-27-2 and are favored by 4½ points, with key players like RB Christian McCaffrey delivering 142 yards from scrimmage last week and WR Ricky Pearsall emerging as a primary outside threat.
- The injuries on both teams could heavily influence strategies and outcomes, as the 49ers seek to start 2-0 for the fourth time under coach Shanahan while the Saints aim to rebound from their opening loss.
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Read Full Article49ers insider suggests reunion with former draft pick amid Brock Purdy injury concerns
The San Francisco 49ers are facing uncertainty at quarterback heading into Week 2 against the New Orleans Saints. Starter Brock Purdy suffered injuries to his left shoulder and toe during Sunday's win over the Seattle Seahawks, with the toe issue reportedly being the greater concern. His practice participation this week will determine his availability. If Purdy can't go, Mac Jones is expected to start. That leaves the question: Who would serve …
Coverage Details
Total News Sources15
Leaning Left5Leaning Right1Center4Last UpdatedBias Distribution50% Left
Bias Distribution
- 50% of the sources lean Left
50% Left
L 50%
C 40%
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