High-resolution imaging shines light on nanoscale nuclear organisation

High-resolution imaging shines light on nanoscale nuclear organisation

Researchers at the Indian Institute of Science (IISc) have implemented an advanced microscopy technique to visualise multiple biomolecules inside the nucleus of a cancer cell simultaneously at incredibly high resolution. The biomolecules they visualised include critical components of the cell’s transcription machinery and proteins that provide structural support to the nucleus – providing one of the first detailed maps of nuclear organisation. T…