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Hepatitis C Vaccine Design Gains Ground as Structures Reveal How Naive
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1 Articles
Hepatitis C Vaccine Design Gains Ground as Structures Reveal How Naive
New structural and biochemical analyses of the hepatitis C virus E2 glycoprotein show that germline-reverted broadly neutralizing antibodies recognize the same conserved epitope as their mature counterparts, guiding engineered immunogen designs and exposing a key constraint in germline-targeting vaccine strategies.
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