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Heart disease may start in the womb, new study finds

Researchers found 10% of offspring exposed to pregnancy hypertension showed higher BMI, blood pressure and early artery damage by age 22.

  • A recent study published in JAMA Network Open suggests poorer cardiovascular health in offspring of mothers who experienced adverse pregnancy outcomes, linking in-utero conditions to long-term heart disease risk.
  • Researchers at Northwestern Medicine evaluated 1,333 mother-child pairs from the Future of Families and Child Well-Being Study, assessing cardiovascular health at approximately 22 years of age to identify long-term in-utero effects.
  • Offspring exposed to HDP exhibited higher BMI , elevated blood pressure , and thicker artery walls , changes researchers equate to three to five years of additional vascular aging.
  • Lead researcher Nilay Shah noted that the child's exposure to these conditions while in utero may influence heart health decades later, calling the discovery "most surprising."
  • Shah encourages parents to prioritize heart-healthy behaviors, noting that "what children learn in childhood sets the stage for their health across their lives.
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14 Articles

The IndependentThe Independent
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Western Morning NewsWestern Morning News
Lean Left

Heart disease risk may start as early as in the womb

Cardiovascular disease is the leading cause of death in America, resulting in nearly 920,000 deaths a year

·London, United Kingdom
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Center

Heart disease may start in the womb, new study finds

Heart disease during pregnancy may be tied to worse heart health in offspring decades later. Here’s what to know.

·Atlanta, United States
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News Medical broke the news in United States on Tuesday, May 19, 2026.
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