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Beta Blockers May Not Be as Beneficial After Heart Attack for some: Study

The REBOOT trial analyzed 8,505 patients and found no overall benefit of beta blockers after mild heart attacks, with a 45% increased risk of adverse events in women, researchers said.

A new study is challenging the idea that beta blockers help everyone who has experienced a heart attack. Researchers at the Spanish National Center for Cardiovascular Research (CNIC) found beta blockers did not offer a clinical benefit for patients whose heart did not deteriorate after the attack.  In an international clinical trial done in collaboration with the Mario Negri Institute for Pharmacological Research in Milan called REBOOT, 8,505 pa…

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The results, which were published simultaneously this Saturday in two articles in the magazines The New England Journal of Medicine and The Lancet, are presented in Madrid at the Congress of the European Society of Cardiology (ESC).The conclusions represent a paradigm shift in the treatment of these patients, since they can modify a medical practice in force for more than 40 years: beta-blockers are widely used after a heart attack, but their us…

‘Reboot’, coordinated by the National Center for Cardiovascular Research (CNIC) in collaboration with the Mario Negri Institute in Milan (Italy), was launched five years ago. Its objective: to determine whether prescribed beta-blockers for life were necessary for the treatments of heart attacks in which heart contraction had not decreased (uncomplicated infarcts). Although the treatment manages to reduce heart rate, blood pressure and contractil…

Having a heart attack tends to force patients to follow a life-long treatment. Pills to keep blood pressure at optimal levels, to control cholesterol, or to prevent blockage of the arteries become the day-to-day for those who have a cardiovascular incident. Among the different medications, beta-blockers are presented as one of the most common in such treatments. A pill that reduces both the frequency and the strength of the beat to minimize bloo…

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hablandoenplata.es broke the news in on Monday, September 1, 2025.
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