US EditionDeadly Brain Cancer Erodes Skull Bone and Alters Immune Marrow
Glioblastoma causes skull bone erosion and shifts skull marrow immune cells toward inflammation, with 15,000 annual U.S. diagnoses highlighting the need for new immune-targeted treatments.
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Deadly brain cancer erodes skull bone and alters immune marrow
Scientists at Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine have shown for the first time that glioblastoma-the deadliest form of brain cancer-affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body's immune response.
Glioblastomas affect much more than just the brain, scientists discover
Scientists at Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine have shown for the first time that glioblastoma—the deadliest form of brain cancer—affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body's immune response. Drugs intended to inhibit skull-bone loss made the cancer more aggressive, according to results published in Nature Neu…
American oncologists have found out why glioblastoma remains one of the most aggressive and untreated forms of cancer. Experiments on mice have shown that the tumor is destroying the skull and bone marrow inside it, which makes the tumor itself even more aggressive, says a paper published in the journal Nature Neuroscence.
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