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Women over the age of 35 could conceive faster with IVF genetic tests: Study

A trial at King's Fertility involving 100 women aged 35-42 showed PGT-A testing led to a 72% live birth rate versus 52% without testing, reducing embryo transfers needed.

  • A 2025 clinical trial conducted by investigators affiliated with King's institutions in London found that genetic screening of embryos created through IVF may enable women aged 35 to 42 to achieve pregnancy more quickly.
  • The trial focused on women over 35 because this group has increasing family starts and a higher risk of embryos with chromosomal abnormalities causing implantation failure and miscarriage.
  • The unblinded pilot study involved 100 women, half given PGT-A to check embryos for correct chromosome numbers, including mosaic embryos rarely studied before.
  • The findings indicated that 72% of women in the PGT-A group had a live birth after up to three embryo transfers, compared to 52% in the control group, with pregnancies occurring more quickly and requiring fewer embryo transfers.
  • Researchers advocate larger multicenter trials to confirm these feasible findings, aiming to reduce emotional and physical IVF burdens for older women.
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Medical Xpress broke the news in on Monday, August 25, 2025.
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