Researchers Identify Genetic 'Convergence' in Autism and a Possible Explanation for the Female Protective Effect
Researchers found one disrupted gene can alter many autism-linked genes, and ZFX may help explain why females are less affected.
4 Articles
4 Articles
Researchers identify specific gene linked to female protection from autism
In many cases all it takes is one mutated gene to orchestrate changes across a whole network of genes linked to autism, according to new results published today in Nature by researchers at Boston Children's Hospital.
Researchers identify genetic 'convergence' in autism and a possible explanation for the female protective effect
In many cases, all it takes is one mutated gene to orchestrate changes across a whole network of genes linked to autism, according to new results published in Nature by researchers at Boston Children's Hospital. The finding could explain why different mutations in one or several of the hundreds of genes linked to autism can lead to a similar condition.
One Autism Mutation Collapses the Whole Gene Network
How can hundreds of different mutations cause autism? Boston Children's Hospital researchers discovered "transcriptomic convergence"—where mutating one autism gene drags down a whole network—and identified ZFX, an X-linked gene that protects females from the collapse.
Hundreds of different genes can increase the risk of autism. How is that possible? Because they are interconnected, American research shows. Autism has a strong genetic component. Scientists have now discovered hundreds of genes that can increase the risk of autism. But that raises a riddle: how can changes in so many different genes lead to […] More science? Read the latest articles on Scientias.nl.
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