Alternative Pathways for Blood Vessel Growth Could Become Targets Against Drug-Resistant Tumors
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4 Articles
Alternative pathways for blood vessel growth could become targets against drug-resistant tumors
Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), together with international collaborators, have uncovered previously unknown mechanisms that allow blood vessels to grow even in the absence of VEGF–VEGFR2 signaling, one of the best-known and most widely targeted pathways in clinical efforts to block tumor angiogenesis, growth and metastasis.
CNIC discovers that blood vessels activate alternative routes of vascular growth in cancer when the VEGF-VEGFR signal is blocked.2 La entrada Vascular growth of cancer: CNIC finds the alternative route that explains resistance to therapies aparece primero en Merca2.
Oncology mariasanchezmonge Study in 'Nature' Blood vessels may continue to grow even in the absence of one of the main pathways that control angiogenesis, according to a team from the National Center for Cardiovascular Research (CNIC) together with international partners.These findings could help explain why tumors develop resistance to antiangiogenic therapies over time and identify alternative mechanisms of angiogenesis as possible new therape…
A team from the Carlos III National Center for Cardiovascular Research (CNIC), together with international collaborators, has discovered hitherto unknown mechanisms that allow the growth of blood vessels even in the absence of VEGF-VEGFR2 signaling, one of the main pathways that regulate angiogenesis.
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