US EditionWhat a Disease in Cats May Teach Us About Long COVID
UNIVERSITY OF CALIFORNIA, DAVIS SCHOOL OF VETERINARY MEDICINE, JUL 14 – UC Davis researchers found that mesenchymal stromal cell therapy combined with antiviral drugs improved immune recovery and reduced inflammation in cats with FIP.
- UC Davis researchers published a study in Stem Cells Translational Medicine showing MSC therapy helps cats recover immune function after severe coronavirus infection.
- This research builds on findings that feline infectious peritonitis , a fatal coronavirus-caused disease in about 2% of cats, disrupts their immune systems similarly to long COVID in humans.
- The study demonstrated that mesenchymal stromal cell therapy combined with the antiviral GS-441524 improved immune recovery and reduced inflammation in a 10-cat pilot trial at UC Davis.
- Amir Kol, corresponding author and UC Davis professor, expressed his amazement at how challenging it is for some to understand working with animals suffering from genuine diseases, and he confirmed that while antiviral treatments ensure survival, mesenchymal stem cell therapy supports immune system recovery.
- These findings suggest veterinary clinical trials offer valuable insights for human long COVID research and NIH plans to expand translational studies involving naturally occurring animal diseases.
11 Articles
11 Articles
What a disease in cats may teach us about long COVID
Feline infectious peritonitis, or FIP, is a serious and historically fatal disease in cats caused by a coronavirus. It behaves in many ways like severe coronavirus infections in humans, causing widespread inflammation, T cell exhaustion, and chronic immune dysfunction.
A clinical trial in cats treated with antivirals and stem cells reveals similarities with the altered immune system of long-term COVID.
Cell Therapy in Cats Sheds Clues on Long COVID
Amir Kol, PhD, associate professor of pathology, microbiology, and immunology at the University of California (UC), Davis, wears two hats. First, as a clinical veterinarian who works closely with students at the local veterinary teaching hospital to analyze samples from dogs, cats, horses, and “every animal that you can think of” for diagnostic training. Second, as a clinical pathologist who applies stem cell biology to address naturally occurri…
Salud a Diario
A team from the University of California at Davis (USA) has developed a cell therapy that, in combination with antiviral drugs, helps the immune system of cats recover and reduce systemic inflammation. The research details are published in STEM CELLS Translational Medicine. According to researchers, this finding, in addition to advancing the treatment of cats with PIF, helps to better understand similar viruses in humans, such as persistent covi…
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