Published 1 month ago • loading... • Updated 1 month ago
Former NFL Player Advocating for Those with Head Injuries Encouraged Answers Are Being Sought
The foundation and Emory University are testing baricitinib in former players, with researchers seeking 30 to 55-year-old men who have depression and cognitive concerns.
The Concussion & CTE Foundation is partnering with Emory University School of Medicine to launch a clinical trial testing whether the FDA-approved medication baricitinib can improve cognitive symptoms in former NFL players.
Chronic traumatic encephalopathy, or CTE, has been found in more than 100 former NFL players, prompting urgent research into how excessive brain inflammation causes neurons to deteriorate and triggers cognitive decline.
Retired 6-year NFL veteran Casey Toohill joined the Concussion & CTE Foundation advisory board last month and is encouraging former teammates to participate, saying "Let's push forward, let's make progress."
Gavegnano of Emory said baricitinib is particularly promising because it is already used for other inflammatory diseases and is considered safe, offering a well-researched approach to potentially restore normal inflammation levels.
CEO Chris Nowinski of the Concussion & CTE Foundation called the collaboration a "special moment" for the scientific community, with the trial seeking adult men ages 30-55 who played tackle football for 11 or more years.