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Estrogen decline alters brain cell matrix in older females

Researchers found estrogen loss in aging female mice changed the brain’s extracellular matrix, a process tied to memory function and Alzheimer’s risk.

Summary by News Medical
A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

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A region between cells in women's brains may hold the key to understanding memory loss associated with declining estrogen after menopause, according to findings from a new preclinical study from Northwestern University School of Medicine in the US. Nearly two-thirds of Americans with Alzheimer's disease are women, but the reasons why they are more vulnerable than men are not yet fully understood. Scientists have long suspected that the loss of e…

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News-Medical.net broke the news on Tuesday, May 26, 2026.
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