Estrogen decline alters brain cell matrix in older females
Researchers found estrogen loss in aging female mice changed the brain’s extracellular matrix, a process tied to memory function and Alzheimer’s risk.
8 Articles
8 Articles
Estrogen decline alters brain cell matrix in older females
A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.
Women's Memory Decline Linked to ECM Changes from Brain Estrogen Loss
New research from investigators at Northwestern Medicine, published in Aging Cell, shows that loss of estrogen production in the brain after menopause is associated with changes in the brain’s extracellular matrix (ECM), a structure between brain cells that supports communication and memory. The findings suggest that estrogen decline may alter hippocampal brain environment in ways that contribute to memory impairment and may help explain why nea…
A region between cells in women's brains may hold the key to understanding memory loss associated with declining estrogen after menopause, according to findings from a new preclinical study from Northwestern University School of Medicine in the US. Nearly two-thirds of Americans with Alzheimer's disease are women, but the reasons why they are more vulnerable than men are not yet fully understood. Scientists have long suspected that the loss of e…
Hidden space between brain cells is now a new Alzheimer’s target
One of the biggest mysteries in neuroscience is why women account for nearly two-thirds of Alzheimer’s disease cases. Now, we may be a step closer to understanding this phenomenon, with new findings that highlight an overlooked part of the brain that appears to fail as estrogen levels fall with age.Continue ReadingCategory: Brain Health, Body and MindTags: Brain, Alzheimer's disease, Menopause, Women's health, Brain, Memory, Cognitive functionin…
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