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Eric Dane to Star in NBC's 'Brilliant Minds' as ALS Patient

Eric Dane plays Matthew, a firefighter with ALS, in Season 2 of NBC's medical drama Brilliant Minds, reflecting his own recent ALS diagnosis, the show airs episodes weekly.

  • On Nov. 24, Eric Dane will guest-star on NBC's Brilliant Minds as Matthew, a firefighter diagnosed with ALS in Season 2, Episode 9 set at Bronx General.
  • Eric Dane disclosed his diagnosis in April, and producers note the casting echoes his ALS diagnosis, adding emotional weight to his role as Matthew.
  • Facing declining mobility, Eric Dane has recently started using a wheelchair and was hospitalized after a fall, causing him to miss the Emmy Awards; he said, `I feel like maybe a couple more months and I won't have my left hand either`.
  • True to his stated mission, Eric Dane uses his platform to raise ALS awareness while filming Euphoria's third season, reflecting his advocacy through his role in Brilliant Minds.
  • Last month, Dane met U.S. Rep. Eric Swalwell to advocate for the 'Push for Progress' plan seeking $1 billion, within the context of the Brilliant Minds series inspired by Oliver Sacks.
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Eric Dane to star in NBC's 'Brilliant Minds' as ALS patient

Dane revealed he was diagnosed with ALS earlier this year.

·Spokane, United States
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Variety broke the news in Los Angeles, United States on Monday, October 20, 2025.
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