Engineered extracellular vesicles facilitate delivery of advanced medicines

Engineered extracellular vesicles facilitate delivery of advanced medicines

Researchers at Karolinska Institutet have developed a technique that enables efficient delivery of therapeutic proteins and RNA to cells. The method, published in Nature Communications, shows promising results in animal studies to deliver gene editors and protein therapeutics.

Engineered Extracellular Vesicles Could Deliver Gene Editors, Therapeutic Proteins to Cells

New research from scientists at the Karolinska Institutet in Sweden and their collaborators elsewhere describes a way of improving extracellular vesicles’ ability to transport things like therapeutic proteins and gene editors into cells. Specifically, their approach involves adding a small part of a bacterial protein called an intein and a fusogenic protein from a virus to the vesicles.  Full details are provided in a new Nature Communications p…

Cutting-Edge Technology Revolutionizes Delivery of Advanced Medicines

In a groundbreaking advancement poised to revolutionize the field of therapeutic delivery, researchers at Sweden’s Karolinska Institutet have unveiled a sophisticated technique that leverages engineered extracellular vesicles (EVs) to efficiently transport therapeutic proteins and RNA into living cells. This promising new method, detailed in a recent article published in Nature Communications, demonstrates significant potential for delivering ge…