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Effect of Penetration Enhancers as Cosurfactants on Transdermal Delivery of Caffeine and Using Microemulsions
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Effect of Penetration Enhancers as Cosurfactants on Transdermal Delivery of Caffeine and Using Microemulsions
Abstract Transdermal drug delivery offers several advantages over conventional routes. However, its use is limited by the low permeability of the stratum corneum. This limitation is especially significant in the case of hydrophilic drugs such as caffeine. This study explored microemulsion systems to enhance the transdermal delivery of caffeine (CF) using chemical penetration enhancers as cosurfactants. Kolliphor® PS80 (PS80), Kolliphor® RH40 (RH…
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