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2026 NFL Playoff Bracket Picks, Score Predictions: 49ers Shock Eagles in Wild Card Round

The 49ers enter the NFC Wild Card game missing top defenders Nick Bosa and Fred Warner, with their defense allowing 24+ points in over half of recent games, per league stats.

  • On Jan. 11, the Philadelphia Eagles will host the San Francisco 49ers at Lincoln Financial Field for a 4:30 p.m. ET kickoff as the defending Super Bowl champions begin their postseason.
  • After late-season losses, San Francisco 49ers settled into the NFC's No. 6 seed, while Philadelphia Eagles finished 11-6 and missed a higher seed after Week 18 outcomes.
  • Defensive stars Nick Bosa and Fred Warner are out for the season, and Tatum Bethune and Dee Winters left the Jan. 3 game, leaving Eric Kendricks and Garret Wallow as primary linebackers.
  • The Eagles will need to beat the 49ers to open the playoffs at home and a Philadelphia win plus a Packers upset would keep them home for the divisional round.
  • Since Week 11, Brock Purdy has completed 70.6% of his passes with 18 touchdowns in his last seven games, while San Francisco averages 30 points and Christian McCaffrey posted 2,126 scrimmage yards.
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Bias Distribution

  • 55% of the sources lean Left
55% Left

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The San Francisco Standard broke the news in on Sunday, January 4, 2026.
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