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Darian Mensah Throws for Two Touchdowns, Nate Sheppard Runs for Two and Duke Routs Syracuse 38-3

Duke gained 503 total yards led by Mensah’s 268 passing yards and Sheppard’s 168 rushing yards in a dominant 38-3 win over Syracuse.

  • On Sep 27, 2025, the Duke Blue Devils football team defeated the Syracuse Orange football team 38-3 at the JMA Wireless Dome, dominating the home offense.
  • With Steve Angeli sidelined, Syracuse turned to Rickie Collins for his first collegiate start, while turnovers by Johntay Cook II, including a controversial recovery, shifted momentum to Duke.
  • Duke's offense piled up yardage, with Nate Sheppard rushing for 168 yards and two touchdowns while Darian Mensah efficiently connected twice with Cooper Barkate.
  • The defeat ended Syracuse's momentum and three-game streak, matching their largest home loss since 2013, while Duke positions as an ACC contender before traveling to Cal next Saturday.
  • Rickie Collins finished his debut with 229 yards passing and an interception, as Syracuse travels to SMU next Saturday to regroup after the loss.
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Darian Mensah throws for two touchdowns, Nate Sheppard runs for two and Duke routs Syracuse 38-3

Duke dominated Syracuse with a 38-3 victory on Saturday, scoring 35 unanswered points. Darian Mensah threw two touchdown passes to Cooper Barkate, while Nate Sheppard ran for two more.

·United States
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Duke 38, Syracuse 3

·Ashtabula, United States
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The Fayetteville Observer broke the news in on Saturday, September 27, 2025.
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