Do proton pump inhibitors prevent ulcers and stomach discomfort caused by non-steroidal anti-inflammatory drugs?

Do proton pump inhibitors prevent ulcers and stomach discomfort caused by non-steroidal anti-inflammatory drugs?

Do proton pump inhibitors prevent ulcers and stomach discomfort caused by non-steroidal anti-inflammatory drugs? Key messages Compared to a placebo (dummy or inactive treatment), proton pump inhibitors probably reduce the development of new ulcers. They also slightly decrease symptoms of dyspepsia (indigestion). They may reduce ulcer complications and probably slightly improve quality of life. They may have little to no harmful effects, but the …