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A warning from the Toronto Zoo CEO: Resurrecting the extinct dire wolf is an ‘incredibly dangerous’ move that comes with ‘enormous’ risk

  • Colossal Biosciences announced the birth of three wolves edited to resemble extinct dire wolves in October 2024 at a managed 2,000-acre preserve in the US.
  • The project started about 18 months earlier using DNA from two ancient fossils and 20 genetic edits to transform the closest living relative, the gray wolf.
  • Experts, including evolutionary biologists, question if these animals truly represent dire wolves given limited genetic similarity and the small number of DNA changes applied.
  • Colossal stated they focus on functional de-extinction of core genes tied to species traits and have taken precautions to avoid harmful genetic effects.
  • The birth signals potential to develop conservation technologies amid accelerating extinctions, though the ecological role and risks of such engineered species remain uncertain.
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US firm says it brought back extinct dire wolves

They whimper, drink from baby bottles and crawl oh so tentatively—they look like cute white puppies, not the fruit of a daring project to resuscitate an extinct species.

·United Kingdom
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elfederalonline.com broke the news in on Tuesday, April 8, 2025.
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