A warning from the Toronto Zoo CEO: Resurrecting the extinct dire wolf is an ‘incredibly dangerous’ move that comes with ‘enormous’ risk
- Colossal Biosciences announced the birth of three wolves edited to resemble extinct dire wolves in October 2024 at a managed 2,000-acre preserve in the US.
- The project started about 18 months earlier using DNA from two ancient fossils and 20 genetic edits to transform the closest living relative, the gray wolf.
- Experts, including evolutionary biologists, question if these animals truly represent dire wolves given limited genetic similarity and the small number of DNA changes applied.
- Colossal stated they focus on functional de-extinction of core genes tied to species traits and have taken precautions to avoid harmful genetic effects.
- The birth signals potential to develop conservation technologies amid accelerating extinctions, though the ecological role and risks of such engineered species remain uncertain.
80 Articles
80 Articles
Dire wolf scientists should know “de-extinction” is a fool’s errand (Opinion)
To breathless media coverage, a company called Colossal Biosciences now claims to have produced three genetically engineered pups of the long-extinct dire wolf. Scientific criticism followed fast. The company’s press release claimed the pups to be “the world’s first de-extinct animals … brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA.” Experts in p…
‘De-extinction’ is a fool’s errand
To breathless media coverage, a company called Colossal Biosciences now claims to have produced three genetically engineered pups of the long-extinct dire wolf. Scientific criticism followed fast. The company’s press release claimed the pups to be “the world’s first de-extinct animals … brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA.” Experts in p…
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