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Depression, Anxiety Increase Heart Disease Risk Through Stress
A study of over 85,500 participants found that having both depression and anxiety raises heart attack and stroke risk by about 32%, linked to brain stress and inflammation.
- Researchers at Mass General Brigham found that depression and anxiety are linked to higher risk of heart attack, heart disease and stroke, reported by HealthDay on Dec. 17.
- Researchers linked biological markers including increased amygdala activity and higher CRP levels to depression and anxiety, Dr. Shady Abohashem reported in Circulation: Cardiovascular Imaging.
- Using data from more than 85,500 participants, researchers followed them for a little over three years during which over 3,000 cardiovascular events occurred, and the associations persisted after adjusting for risk factors.
- For clinicians, the study is a reminder that mental health must be part of cardiovascular risk assessment, while researchers note the observational design cannot prove cause and effect.
- The study suggests that combined mood disorders increase risk, with people with both depression and anxiety facing roughly 32% higher risk, forming a biological chain linking emotional stress to heart risk.
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20 Articles
Depression Quietly Damages the Heart Through Stress Circuits
Summary: Depression and anxiety may heighten cardiovascular disease risk through chronic stress pathways in the brain and body. In a large analysis of more than 85,000 adults, those with depression or anxiety — especially both — were significantly more likely to experience heart attack, stroke or…
Coverage Details
Total News Sources20
Leaning Left5Leaning Right3Center3Last UpdatedBias Distribution46% Left
Bias Distribution
- 46% of the sources lean Left
46% Left
L 46%
C 27%
R 27%
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