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Study in Nature Medicine Finds Taking Centrum Silver Daily May Slow Biological Aging

A two-year trial found daily multivitamins slowed biological aging by about four months, with greater effects in older adults showing accelerated aging at baseline.

  • A randomized COSMOS analysis published Monday showed daily multivitamins were associated with about four months' less biological aging over two years, based on 958 participants with an average age around 70.
  • Researchers used five epigenetic clocks including second-generation models to analyse DNA methylation biomarkers in blood samples from the COSMOS trial randomization into four pill groups.
  • Measured by specific clocks, PCPhenoAge slowed aging by about 2.6 months and PCGrimAge by about 1.4 months, while participants with accelerated biological age at baseline saw PCGrimAge slow by about 2.8 months.
  • Experts caution that effect sizes are modest, and Sesso said, 'Rather, this is starting to provide the connecting dots', advising decisions be made with healthcare providers.
  • Researchers plan follow-up analyses to see whether clock changes persist and link to clinical outcomes such as cognition, cancer or cataracts, Yanbin Dong, MD, Ph.D., said; if validated, daily multivitamins could be a cost-efficient intervention with small cancer-risk reductions over 10 years.
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A startling study has been published in the journal Nature Medicine. According to the study, a common multivitamin tablet has the ability to slow down aging. But how big is the effect – and how do you actually measure “biological aging”? DN's science reporter Johan Nilsson finds out what's going on.

·Stockholm, Sweden
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A study conducted by researchers at Massachusetts General Hospital, within the Mass General Brigham system in the United States, has found that taking a multivitamin daily for two years can slow biological aging in older adults. The analysis, published in Nature Medicine magazine, evaluated five cell markers of aging and found a slowdown equivalent to about four months from normal rhythm, with particularly noticeable effects on people who at the…

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Nature broke the news in United Kingdom on Monday, March 9, 2026.
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