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Daewoong Pharmaceutical Presents Phase 2 Clinical Trial Poster on 'Bersiporocin' at ATS 2025, Highlights Global Patient Demographics
On June 3, 2025, Daewoong Pharmaceutical shared interim findings from a global Phase 2 trial of Bersiporocin involving 102 idiopathic pulmonary fibrosis participants recruited across the United States and South Korea.
The randomized, double-blind, placebo-controlled study aims to suppress fibrosis progression by selectively inhibiting collagen synthesis via PRS targeting amid a racially diverse population.
Approximately 70% of participants received Bersiporocin with approved antifibrotics nintedanib or pirfenidone, while more than 50% of patients are Asian, enabling assessment across ethnic subgroups.
Bersiporocin, granted Orphan Drug and Fast Track designations by the FDA, inhibits Prolyl-tRNA Synthetase to target fibrosis at its origin, with Professor Song stating the trial offers hope and diversity in treatment responses.
Daewoong's CEO Seongsoo Park highlighted Bersiporocin as a pioneering antifibrotic treatment targeting the underlying cause of fibrosis and emphasized their dedication to further developing this initiative to transform global approaches to IPF therapy.