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CStone Announces First Patient Dosed in Global Multicenter Phase I Clinical Trial of CS2009, a PD-1/VEGF/CTLA-4 Trispecific Antibody

  • CStone Pharmaceuticals announced that the first patient has been dosed in a global Phase I trial of CS2009, a trispecific antibody, with no adverse effects reported.
  • The trial aims to evaluate CS2009's effectiveness against various advanced solid tumors, including lung cancer and cervical cancer.
  • CS2009 targets PD-1, VEGFA, and CTLA-4, potentially improving treatment for patients with low or negative PD-L1 expression.
  • Dr. Jason Yang, CStone CEO, stated that this study marks a breakthrough in their clinical development efforts for innovative therapies.
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Brattleboro Reformer broke the news in on Tuesday, March 4, 2025.
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