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Crispr without Scissors: the Epigenetic Editing that Turns Genes Off and on without Cutting Dna
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Over the last decade, CRISPR has become the most famous “searcher and replacer” of biology. In its classic version, it finds a concrete sequence of DNA and cuts it to deactivate a gene or to try to correct it. That gesture — cutting— is powerful, but also delicate: when you open a double propeller like the one who does a work at home, there is a risk that cracks will appear in walls that you did not want to touch. A UNSW Sydney team proposes an …
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