How Brain Cells Meant to Help May Be Making Depression Worse

How brain cells meant to help may be making depression worse

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed by microglia—as major players in neuroinflammation that drives depression. These star-shaped brain cells, once thought to only support neurons, are now shown to regulate communication between brain cells and even trigger or amplify inflammatory res…

Relative synonymous codon usage and codon pair analysis of depression associated genes

Depression negatively impacts mood, behavior, and mental and physical health. It is the third leading cause of suicides worldwide and leads to decreased quality of life. We examined 18 genes available at the genetic testing registry (GTR) from the National Center for Biotechnological Information to investigate molecular patterns present in depression-associated genes. Different genotypes and differential expression of the genes are responsible f…

Could Treating Inflammation Be a Three-in-One Intervention for Allergy, Asthma, and Depression?

Early exposure to environmental immunoregulatory organisms such as microbes, parasites, and other animals may suppress inflammation and the development of asthma, allergies, and some types of depression. Medscape Medical News

Inflammation Link Allergy, Asthma, and Depression?

The prevalence of depression is consistently higher in persons with asthma than in persons without it, according to experts, and a review of 24 studies also found that allergic rhinitis was associated with higher odds of depression or anxiety. Over the past two decades, multiple investigators have looked beyond emotional or lifestyle triggers of depression […] The post Inflammation Link Allergy, Asthma, and Depression? first appeared on News Hea…