A cheap antidepressant could help treat incurable brain tumours, early studies show
- Researchers at ETH Zurich discovered that the antidepressant vortioxetine kills glioblastoma tumor cells in lab tests.
- Vortioxetine crosses the blood-brain barrier, making it a promising treatment option, according to Professor Berend Snijder.
- Trials at University Hospital Zurich showed vortioxetine's effectiveness in mice with glioblastomas, suggesting potential for real-world treatment.
18 Articles
18 Articles
Promising antidepressant offers hope for glioblastoma treatment
Glioblastoma is a particularly aggressive brain tumor that at present is incurable. Cancer doctors can extend patients' life expectancy through operations, radiation, chemotherapy or surgical interventions. Nevertheless, half of patients die within twelve months of diagnosis.
Potential Cancer Breakthrough: Common Antidepressant Effective Against Brain Tumors
Vortioxetine, an antidepressant, shows promise against glioblastoma in lab tests conducted by ETH Zurich, leading to forthcoming clinical trials. Glioblastoma is an incurable and fatal type of brain cancer. In a large-scale drug screening, the antidepressant, vortioxetine emerged as one of the most effective agents against these types of cancer cells. Clinical trials are already [...]

Common antidepressant ‘unexpectedly effective’ against aggressive brain tumours
Findings raise hope for treating a disease which as a poor survival rate.

Antidepressant shows promise for treating brain tumors
Glioblastoma is a particularly aggressive brain tumor that at present is incurable. Cancer doctors can extend patients' life expectancy through operations, radiation, chemotherapy or surgical interventions. Nevertheless, half of patients die within twelve months of diagnosis.
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