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Christina Applegate Shares She's Mostly Confined to Her Bedroom Amid MS Battle

Applegate details living with multiple sclerosis, including chronic pain and the impact on her 15-year-old daughter, while promoting her memoir releasing March 3.

  • In a People interview published Tuesday, Christina Applegate said that ongoing MS pain has left her largely confined to her bed, but she still drives her daughter Sadie to school.
  • Applegate was diagnosed in August 2021 with multiple sclerosis, a neurological disease causing weakness and vision problems, and will detail her health in the memoir You With the Sad Eyes, due March 3.
  • Applegate describes coping methods including nicknaming body parts like Barbara and Stan, and says she has 30 lesions on her brain and has been hospitalized with severe pain.
  • Applegate said the illness has changed her career, describing how she is probably not going to work on-camera again and launched Next in MS earlier this month to support others.
  • Applegate frames her account with blunt honesty, saying `My life isn't wrapped up with a bow` and recalls being told, `You need to get checked for MS`, as she raises awareness.
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Christina Apple revealed that she is now in most of the conditioned bed, five years after she was diagnosed with multiple sclerosis.

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Christina Applegate revealed that she was most often confined to bed because of the pain caused by her multiple sclerosis.

·Montreal, Canada
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In 2021 Christina Applegate received the diagnosis of multiple sclerosis. Since then, the incurable disease has shaped the life of the "A terrible nice family" star. Now the condition of the actress has deteriorated again.

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The Independent broke the news in London, United Kingdom on Tuesday, February 24, 2026.
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