US EditionJamie-Lynn Sigler to Play Doctor with MS on ‘Grey’s Anatomy’
Jamie-Lynn Sigler returns to TV after three years to portray a urologist with multiple sclerosis, a role created to reflect her real-life advocacy and experiences.
- On January 15, Jamie-Lynn Sigler appears on Grey's Anatomy as Dr. Laura Kaplan in Episode 2208 'Heavy on Me', marking her return to TV after three years.
- Producers created the role specifically for Jamie-Lynn Sigler, actress and MS advocate, who was diagnosed with multiple sclerosis in 2002 and went public in 2016 after hiding it for 15 years.
- Sigler confirmed the casting on Thursday via Instagram, sharing a first look at her character who visits Grey Sloan at Dr. Catherine Fox's request to advise Dr. Richard Webber.
- The decision increases public visibility for MS and connects to Jamie-Lynn Sigler's advocacy, including her MeSsy podcast with Christina Applegate and recent public remarks.
- Ahead of Grey's Anatomy returning on Jan. 8, 2026, Sigler lines up both TV and publishing projects, including an indie thriller and a HarperCollins memoir.
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Jamie-Lynn Sigler to Play Doctor with MS on ‘Grey’s Anatomy’
The 'Sopranos' alum has lived with MS for more than two decades.
'The Sopranos' star Jamie-Lynn Sigler set to appear in 'Grey's Anatomy'
Jamie-Lynn Sigler is returning to television with a powerful new role on ABC's Grey's Anatomy.The Sopranos alum will appear as Dr. Laura Kaplan, a urologist living with Multiple Sclerosis who visits Grey Sloan Memorial at the request of...
Jamie-Lynn Sigler to play doctor with MS on 'Grey's Anatomy' amid real-life battle with disease
Sigler will appear in a January episode as Dr. Laura Kaplan, a urologist with multiple sclerosis.Michael Loccisano/Getty Jamie-Lynn Sigler in New York City on June 13Jamie-Lynn Sigler is returning to the small screen.Three years since her last time on TV, Sigler has staked out a major comeback with an upcoming guest role on Grey's Anatomy. Sigler will portray Dr. Laura Kaplan, a urologist living with MS, in the Jan. 15 episode "Heavy on Me." The…
Grey's Anatomy Casts The Sopranos Star in Season 22
Photo Credit: ABC Grey’s Anatomy Season 22 is expanding its cast with The Sopranos alum Jamie-Lynn Sigler. According to a new report, the actress, who is battling multiple sclerosis, will guest-star in an episode that will air in January 2026. Jamie-Lynn Sigler joins Grey’s Anatomy Season 22 cast as doctor with MS Jamie-Lynn Sigler has joined the cast of Grey’s Anatomy Season 22 as Dr. Laura Kaplan, Deadline reported. The character will debut in…
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