Caltech Researchers Upend Decades-Old Model of Mitochondrial Protein Import

Caltech Researchers Upend Decades-Old Model of Mitochondrial Protein Import

Researchers showed that many mitochondrial proteins enter the organelle during synthesis, guided by folding patterns and structural signals. This discovery revises decades of biochemical models. Mitochondria are organelles most commonly known as the “powerhouses of the cell” because they generate ATP (adenosine triphosphate), the main energy source for most cellular activities. They originated more than [...]