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Breast Cancer Scientific Study Breakthrough for New Antibody Treatment
- On October 23, 2025, researchers at King's College London reported a novel antibody that attacks tumour cells and harnesses the body's immune defenses, publishing their findings in Cancer Research journal.
- Triple-Negative breast cancer lacks receptors for oestrogen, progesterone and HER2, making hormone therapies and HER2 drugs ineffective and leaving patients with fewer treatment options and higher recurrence risk.
- Preclinical studies found the antibody bound immune cells more strongly and activated immune cells within tumours and circulating immune cells in lab and animal studies.
- The research team at King's College London says the therapy could provide new options for treatment-resistant cancers, including triple-negative cases, and might extend to ovarian and endometrial cancers; further lab optimisation tasks are under way to extend antibody lifespan and broaden immune activation before clinical trials.
- This early-stage research offers hope for over 8,000 women in the UK diagnosed with triple-negative breast cancer, which accounts for around 15% of all breast cancers and affects younger women and Black women more.
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42 Articles
42 Articles
Wales Online+2 Reposted by 2 other sources
New breast cancer treatment breakthrough shows promise
Scientists have developed a new antibody that can limit the growth of treatment-resistant breast cancers
·Wales, United Kingdom
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Total News Sources42
Leaning Left7Leaning Right4Center10Last UpdatedBias Distribution48% Center
Bias Distribution
- 48% of the sources are Center
48% Center
L 33%
C 48%
R 19%
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