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Brain pathway may explain higher depression rates in teen girls

Summary by Medical Xpress
Depression is a mental health condition that affects 280 million people worldwide. It is twice as common in women than men and this pattern starts to develop during adolescence. Researchers have studied the biological processes that drive depression in adults and have shown a potential role for the kynurenine pathway, but this is the first time it has been investigated in adolescents in relation to biological sex.

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"Depression is a mood disorder that results in loss of motivation, lack of self-esteem and self-confidence," recalls the Medical Research Foundation. "It causes suffering.

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Medical Xpress broke the news in on Tuesday, March 25, 2025.
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