State-of-the-Art Microchips Help Understand How Sepsis and Neurodegenerative Diseases Damage the Brain

State-of-the-art microchips help understand how sepsis and neurodegenerative diseases damage the brain

In lieu of animal experiments, researchers from the University of Rochester are using state-of-the-art microchips with human tissue to better understand how the brain operates under healthy conditions and is damaged through neurodegenerative diseases or conditions like sepsis.

Brain-on-a-chip technology reveals how sepsis and neurodegenerative diseases damage the brain

In lieu of animal experiments, researchers from the University of Rochester are using state-of-the-art microchips with human tissue to better understand how the brain operates under healthy conditions and is damaged through neurodegenerative diseases or conditions like sepsis.

Human Brain-on-a-Chip Reveals How Inflammation Breaks the Mind

Researchers have developed brain-on-a-chip technology that uses human tissue to model how the brain’s protective barrier breaks down during inflammation and disease. The system replicates the blood-brain barrier, showing how cytokine storms and leaked blood proteins can trigger harmful changes in brain cells.

Brain-on-a-Chip Shows How Inflammation Damages the Blood-Brain Barrier

Researchers at the University of Rochester have developed and tested a state-of-the-art microchip embedded with human tissue that replicates key features of the human blood-brain barrier (BBB) to better understand how the brain operates under healthy conditions and is damaged through neurodegenerative diseases or conditions like sepsis. The new brain-on-a-chip technology simulates how the blood-brain barrier responds to both systemic inflammatio…