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Brain Immune Cells Found to Regulate Anxiety and Grooming Behaviors
Researchers found that raising calcium in Hoxb8 microglia triggered anxiety and grooming, while blocking calcium entry prevented both behaviors in mice.
A study led by a University of Louisville School of Medicine pediatrics and child neurology researcher reveals how a specific signaling mechanism in microglia, the brain's immune cell, can regulate anxiety and grooming behaviors. These behaviors are core symptoms of autism and obsessive-compulsive spectrum disorders.