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'Bone glue': China unveils 3-minute fracture treatment

  • Researchers at Sungkyunkwan University created a specialized glue gun device that enables 3D printing of biodegradable bone implants precisely at the site of fractures and bone defects during surgical procedures using a composite filament.
  • This innovation overcomes difficulties in managing irregular or large fractures without relying on pre-made implants, leading to shorter surgery durations and enhanced workflow effectiveness in practical operating environments.
  • The composite filament consists of hydroxyapatite, which enhances bone cell attachment and regeneration, and polycaprolactone, which liquefies at low temperatures to prevent tissue damage and support scaffold longevity.
  • In tests involving rabbits with critical defects in their femur, the 3D-printed scaffold demonstrated no signs of infection or toxicity, promoted faster and more robust bone regrowth compared to traditional bone cement, and effectively suppressed E. coli and S. aureus through the gradual release of embedded vancomycin and gentamicin.
  • The technology offers potential for personalized, in situ bone repair, but clinical adoption requires standardized manufacturing, validated sterilization, and preclinical large animal studies to meet regulatory standards.
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New Atlas broke the news in on Tuesday, September 9, 2025.
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