Boehringer's zongertinib shows encouraging efficacy and tolerability profile in previously treated HER2 mutated lung cancer patients - Pipelinereview

pipelinereview

Boehringer's zongertinib shows encouraging efficacy and tolerability profile in previously treated HER2 mutated lung cancer patients - Pipelinereview

Beamion LUNG-1, Phase Ib met its primary endpoint, demonstrating a meaningful objective response rate (ORR) of 66.7%, as assessed by blinded independent central review (BICR)1 Preliminary activity in patients with brain metastases were also observed, with an intracranial response of 33% and 74% disease control rate (DCR) Zongertinib was generally well tolerated, with mostly mild and manageable treatment related adverse events (TRAE) and low disc…