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Trial of Boehringer's cystic fibrosis gene therapy imminent

Summary by Pharmaphorum
Boehringer's cystic fibrosis gene therapy is poised to start clinical testing, hoping to offer a one-shot alternative to costly CFTR modulator drugs.
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Inside Precision MedicineInside Precision Medicine

First-in-Human Trial of Inhalable Gene Therapy for Cystic Fibrosis Begins

A new inhalable gene therapy for cystic fibrosis (CF), BI 3720931, is being tested in a human trial across the U.K. and Europe. The trial, named LENTICLAIR 1, aims to determine the safety, tolerability, and efficacy of the treatment, particularly for patients who do not respond to CFTR modulator therapies. The study is sponsored by Boehringer Ingelheim in collaboration with the UK Respiratory Gene Therapy Consortium and OXB (formerly Oxford Biom…

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PharmaphorumPharmaphorum

Trial of Boehringer's cystic fibrosis gene therapy imminent

Boehringer's cystic fibrosis gene therapy is poised to start clinical testing, hoping to offer a one-shot alternative to costly CFTR modulator drugs.

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Clinical Trials ArenaClinical Trials Arena

Boehringer and partners commence gene therapy trial for cystic fibrosis

Boehringer Ingelheim and partners have commenced the Phase I/II LENTICLAIR 1 trial of gene therapy BI 3720931 targeting cystic fibrosis (CF).The post Boehringer and partners commence gene therapy trial for cystic fibrosis appeared first on Clinical Trials Arena.

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Clinical Trials Arena broke the news in on Friday, February 21, 2025.
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