BLOOD TEST MAY HELP PREDICT RISK OF COGNITIVE DECLINE DUE TO ALZHEIMER'S A DECADE BEFORE SYMPTOMS APPEAR
Researchers said very high p-tau217 levels were linked to a 78% risk of cognitive impairment within 10 years in symptom-free older adults.
- On Wednesday, July 15, 2026, researchers presented findings at the Alzheimer's Association International Conference in London showing a blood test detecting P-tau217 can predict future cognitive impairment in symptom-free older adults.
- Researchers analyzed data from nearly 2,700 cognitively unimpaired adults, average age 70, across six major Alzheimer's research groups; the study was simultaneously published in JAMA to examine P-tau217's prognostic value.
- Cognitively healthy older adults with very high P-tau217 levels faced an approximately 78% risk of developing cognitive impairment over 10 years, while those with moderate elevations faced 45% risk over the same period.
- "Once verified, these blood tests could be used to recruit patients for clinical trials," said Rachel F. Buckley, Ph.D., lead author at the Mass General Brigham Neuroscience Institute, noting potential for guiding treatment decisions.
- Maria C. Carrillo, Ph.D., Alzheimer's Association chief science officer, said identifying risk earlier could fundamentally change dementia prevention, though researchers cautioned P-tau217 alone cannot fully predict future risk without other factors.
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Study Shows a Blood Test Can Help Identify Healthy People at High Risk for Alzheimer’s Disease
WASHINGTON (AP) — A blood test may predict if apparently healthy older adults are likely to develop Alzheimer’s symptoms in the next five or 10 years, researchers reported Wednesday. That information could be reassuring or terrifying, but for now it’s a potential tool to speed drug development by helping to identify and enroll high-risk people […]
The test is not yet recommended for people without symptoms because, at the moment, there are no effective preventive treatments
Blood Test Predicts Alzheimer's Risk Years Into the Future
A simple vial of blood may soon help forecast who develops Alzheimer's—and when. New research unveiled at this week's Alzheimer's Association International Conference in London suggests blood tests that measure amyloid and tau proteins can sharply improve diagnosis in people with memory problems and estimate future risk in those...
Shafaq News – Follow-up: Researchers reported on Wednesday that a blood test may be able to predict whether seemingly healthy older adults are at risk of developing Alzheimer's disease within the next five to ten years. While this information may be reassuring to some and alarming to others, it currently represents a potential tool for accelerating drug development by helping identify those most at risk and involving them in studies of potential…
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