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B.C. Teen Becomes First Person Cured by Prime Editing
Prime editing cured Ty Sperle's rare chronic granulomatous disease, offering hope as one in three hospital admissions involve rare diseases, BC Children's Hospital says.
- Ty Sperle, a 19-year-old from Kelowna, was cured of a rare genetic disease using prime editing, as reported in the New England Journal of Medicine last December, and learned he was cured 'that day last year.'
- Dr. Stuart Turvey says chronic granulomatous disease leaves patients vulnerable to serious infections, and many lack an optimal donor, facing chemotherapy, bone-marrow transplant, or daily antibiotics and antifungals.
- Researchers extracted Sperle's autologous cells, corrected the 'spelling mistake' in DNA, and reinserted the cells so they multiplied; the clinical trial was offered only at Montreal's Sainte-Justine university hospital.
- Provincial health minister Josie Osborne called the treatment a 'milestone' as Sperle no longer needs daily medication or fears severe infections, Turvey said it's a 'dream come true.'
- The therapy is not yet routinely available and delivering it across health-care systems requires complex steps; clinicians say Sperle's case proves prime editing offers hope for many rare diseases, which affect about one in three hospital admissions at BC Children's Hospital.
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The Toronto Star+25 Reposted by 25 other sources
B.C. man cured of rare disease in world-first for new gene-editing technology
Ty Sperle says he felt "insane shock" after learning he'd been cured of a rare genetic disease through a clinical trial using a new gene-editing treatment.
·Toronto, Canada
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B.C. man cured of rare disease in world-first for new gene-editing technology – Energeticcity.ca
Ty Sperle says he felt “insane shock” after learning he’d been cured of a rare genetic disease through a clinical trial using a new gene-editing treatment. The B.C. man says he’d started that day last year feeling hopeless, but the news he was cured filled him with indescribable happiness. Sperle is the first person known to have received and be cured by a treatment known as “prime editing,” in a breakthrough by U.S.-based Prime Medicine reporte…
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Total News Sources30
Leaning Left18Leaning Right1Center6Last UpdatedBias Distribution72% Left
Bias Distribution
- 72% of the sources lean Left
72% Left
L 72%
C 24%
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