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Artificial sweeteners aged the brain by over 1.5 years, study says

A study of 12,772 Brazilians found adults under 60 who consumed the most artificial sweeteners experienced a 62% faster decline in memory and cognition over eight years.

  • Recently, the Neurology paper reports a study linking higher artificial sweetener intake to 62% faster cognitive decline among 12,772 adults from Brazil over an average of eight years.
  • The researchers examined seven sweeteners, including aspartame and saccharin, which are common in food products and used as standalone sweeteners, as their long-term brain effects were not well characterized.
  • By consumption tier, the middle-consumption group showed a 35% faster cognitive decline, equivalent to about 1.3 years, while the highest-consumption group averaged 191 mg/day and the lowest-consumption group 20 mg/day.
  • Regulatory bodies like the FDA continue to approve sweeteners, despite experts warning that the study shows an association, not causation, and Dr. Claudia Kimie Suemoto emphasized caution.
  • Researchers pointed to potential biological mechanisms like neuroinflammation, neurodegeneration and gut-brain axis disruption, while this year's studies linked sweeteners to diabetes, cardiovascular disease and stroke risks.
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A study recently published in the journal Neurology found that some sugar substitutes, present in processed foods and some even commonly used, may have long-term consequences in the brain. Researchers examined seven sweeteners that do not contain or are low in calories, through an observational study, and the results indicate a relationship between their consumption and faster cognitive impairment. Among those under 60, those who consumed the hi…

·Chile
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Although a recent study did not show a direct correlation, researchers say that zero-calorie sweeteners can age our brains by 1.6 extra years.

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Sugar Substitutes Could Be Bad For Brain Aging, Study Argues

·New York, United States
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Newsweek broke the news in United States on Wednesday, September 3, 2025.
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